Contribution of both B-cell intrinsic alterations as well as non-hematopoietic-derived factors in the enhanced immune response of the NOD mouse

• Главные авторы: Viqar Showkat Banday (Автор), Radha Thyagarajan (Автор), Kristina Lejon (Автор)
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• Опубликовано: Taylor & Francis Group, 2017-08-01T00:00:00Z.
• Предметы: article
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The underlying cellular and molecular mechanism for the development of Type 1 diabetes is still to be fully revealed. We have previously demonstrated that the NOD mouse, a model for Type 1 diabetes, display a prolonged and enhanced immune response to both self and non-self-antigens. The molecular ex...