Contribution of both B-cell intrinsic alterations as well as non-hematopoietic-derived factors in the enhanced immune response of the NOD mouse

• Główni autorzy: Viqar Showkat Banday (Autor), Radha Thyagarajan (Autor), Kristina Lejon (Autor)
• Format: Książka
• Wydane: Taylor & Francis Group, 2017-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The underlying cellular and molecular mechanism for the development of Type 1 diabetes is still to be fully revealed. We have previously demonstrated that the NOD mouse, a model for Type 1 diabetes, display a prolonged and enhanced immune response to both self and non-self-antigens. The molecular ex...