TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2

• मुख्य लेखकों: Raquel Rodrigues-Díez (लेखक), Sandra Rayego-Mateos (लेखक), Macarena Orejudo (लेखक), Luiz Stark Aroeira (लेखक), Rafael Selgas (लेखक), Alberto Ortiz (लेखक), Jesús Egido (लेखक), Marta Ruiz-Ortega (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2015-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The CCN family member 2 (CCN2, also known as connective tissue growth factor) may behave as a risk biomarker and a potential therapeutic target for renal disease. CCN2 participates in the regulation of inflammation and fibrosis. TGF-β is considered the main fibrogenic cytokine; however, in some path...