TGF-Beta Blockade Increases Renal Inflammation Caused by the C-Terminal Module of the CCN2

• Hoofdauteurs: Raquel Rodrigues-Díez (Auteur), Sandra Rayego-Mateos (Auteur), Macarena Orejudo (Auteur), Luiz Stark Aroeira (Auteur), Rafael Selgas (Auteur), Alberto Ortiz (Auteur), Jesús Egido (Auteur), Marta Ruiz-Ortega (Auteur)
• Formaat: Boek
• Gepubliceerd in: Hindawi Limited, 2015-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

The CCN family member 2 (CCN2, also known as connective tissue growth factor) may behave as a risk biomarker and a potential therapeutic target for renal disease. CCN2 participates in the regulation of inflammation and fibrosis. TGF-β is considered the main fibrogenic cytokine; however, in some path...