Preparation and physicochemical characterization of prazosin conjugated PLGA nanoparticles for drug delivery of flutamide

• Asıl Yazarlar: Ali Fattahi (Yazar), Mansoureh Ghiasi (Yazar), Pardis Mohammadi (Yazar), Leila Hosseinzadeh (Yazar), Khosro Adibkia (Yazar), Ghobad Mohammadi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Universidade de São Paulo, 2019-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

In the current work, a sustained drug delivery system of flutamide (FLT) was developed using Poly(D,L-lactide-co-glycolide) (PLGA) decorated bypoly(ethylene glycol) (PEG) grafted prazosin (PLGA-PEG-Praz) as a targeting moiety. In a multi-step reaction, PLGA was linked to PEG and prazosin. The struct...