Drug Discovery of DKK1 Inhibitors

• Hoofdauteurs: Hewen Jiang (Auteur), Zongkang Zhang (Auteur), Yuanyuan Yu (Auteur), Hang Yin Chu (Auteur), Sifan Yu (Auteur), Shanshan Yao (Auteur), Ge Zhang (Auteur), Bao-Ting Zhang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Dickkopf-1 (DKK1) is a well-characterized Wnt inhibitor and component of the Wnt/β-catenin signaling pathway, whose dysregulation is associated with multiple abnormal pathologies including osteoporosis, Alzheimer's disease, diabetes, and various cancers. The Wnt signaling pathway has fundamenta...