Drug Discovery of DKK1 Inhibitors

• Главные авторы: Hewen Jiang (Автор), Zongkang Zhang (Автор), Yuanyuan Yu (Автор), Hang Yin Chu (Автор), Sifan Yu (Автор), Shanshan Yao (Автор), Ge Zhang (Автор), Bao-Ting Zhang (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Dickkopf-1 (DKK1) is a well-characterized Wnt inhibitor and component of the Wnt/β-catenin signaling pathway, whose dysregulation is associated with multiple abnormal pathologies including osteoporosis, Alzheimer's disease, diabetes, and various cancers. The Wnt signaling pathway has fundamenta...