Optimization of a Cefuroxime Axetil-Loaded Liquid Self-Nanoemulsifying Drug Delivery System: Enhanced Solubility, Dissolution and Caco-2 Cell Uptake

Cefuroxime axetil (CA) is an oral cephalosporin which hydrolyzes rapidly to the active parent compound cefuroxime. CA is known to have incomplete oral bioavailability (30-50%) due to its poor solubility and enzymatic conversion to cefuroxime in the gut lumen. In order to overcome these drawbacks, a...

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Main Authors: Arshad Ali Khan (Author), Akhtar Atiya (Author), Safia Akhtar (Author), Yogesh Yadav (Author), Kamal A. Qureshi (Author), Mariusz Jaremko (Author), Syed Mahmood (Author)
Format: Book
Published: MDPI AG, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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