Bioavailability of a novel sustained‐release pellet formulation of 5‐flucytosine in healthy‐fed participants for use in patients with cryptococcal meningitis

• मुख्य लेखकों: Nabila Ibnou Zekri Lassout (लेखक), Vishal Goyal (लेखक), Edrich Krantz (लेखक), Francois Simon (लेखक), Anouk Neven (लेखक), Johanna Eriksson (लेखक), Amaria Saayman (लेखक), Vijay Satam (लेखक), Carol Ruffell (लेखक), Sarika Victor (लेखक), Marylore Chenel (लेखक), Aljosa Celebic (लेखक), Henri Caplain (लेखक), Jean‐Yves Gillon (लेखक), Abhijit Deshmukh (लेखक), Amit Antarkar (लेखक), Eric Sjögren (लेखक), Isabela Ribeiro (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Wiley, 2024-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Cryptococcal meningoencephalitis (CM) is an opportunistic fungal infection and a major cause of death among people living with human immunodeficiency virus in sub‐Saharan Africa. 5‐flucytosine (5‐FC) is a unique, brain‐permeable antifungal agent used to reduce mortality from CM and to preve...