Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart
Radiolabelled antagonistic bombesin analogues are successfully used for targeting of gastrin-releasing peptide receptors (GRPR) that are overexpressed in prostate cancer. Internalization of antagonistic bombesin analogues is slow. We hypothesized that the use of a non-residualizing radioiodine label...
Saved in:
Main Authors: | Maryam Oroujeni (Author), Ayman Abouzayed (Author), Fanny Lundmark (Author), Bogdan Mitran (Author), Anna Orlova (Author), Vladimir Tolmachev (Author), Ulrika Rosenström (Author) |
---|---|
Format: | Book |
Published: |
MDPI AG,
2019-08-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Heterodimeric Radiotracer Targeting PSMA and GRPR for Imaging of Prostate Cancer-Optimization of the Affinity towards PSMA by Linker Modification in Murine Model
by: Fanny Lundmark, et al.
Published: (2020) -
Preclinical Evaluation of <sup>99m</sup>Tc-Labeled GRPR Antagonists maSSS/SES-PEG<sub>2</sub>-RM26 for Imaging of Prostate Cancer
by: Ayman Abouzayed, et al.
Published: (2021) -
Design, Synthesis, and Evaluation of Linker-Optimised PSMA-Targeting Radioligands
by: Fanny Lundmark, et al.
Published: (2022) -
Synthesis and Preclinical Evaluation of Radio-Iodinated GRPR/PSMA Bispecific Heterodimers for the Theranostics Application in Prostate Cancer
by: Ayman Abouzayed, et al.
Published: (2019) -
Improved Radiolytic Stability of a <sup>68</sup>Ga-labelled Collagelin Analogue for the Imaging of Fibrosis
by: Irina Velikyan, et al.
Published: (2021)