Rapid and sensitive analysis of melatonin by LC-MS/MS and its application to pharmacokinetic study in dogs

• Asıl Yazarlar: Huimin Zhao (Yazar), Yifei Wang (Yazar), Yi Jin (Yazar), Shu Liu (Yazar), Haiyan Xu (Yazar), Xiumei Lu (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2016-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

A rapid and sensitive liquid chromatography tandem mass spectrometry method was established and validated for determination of melatonin in dog plasma using desvenlafaxine as an internal standard (IS). Plasma samples were pretreated by liquid-liquid extraction with ethyl acetate. Chromatographic sep...