Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids

• Autori principali: Donatella Fiore (Autore), Prashanthi Ramesh (Autore), Maria C. Proto (Autore), Chiara Piscopo (Autore), Silvia Franceschelli (Autore), Serena Anzelmo (Autore), Jan P. Medema (Autore), Maurizio Bifulco (Autore), Patrizia Gazzerro (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Colorectal cancer (CRC), like other tumor types, is a highly heterogeneous disease. Within the tumor bulk, intra-tumoral heterogeneity is also ascribable to Cancer Stem Cells (CSCs) subpopulation, characterized by high chemoresistance and the unique ability to retain tumorigenic potential, thus asso...