Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids

• Autors principals: Donatella Fiore (Autor), Prashanthi Ramesh (Autor), Maria C. Proto (Autor), Chiara Piscopo (Autor), Silvia Franceschelli (Autor), Serena Anzelmo (Autor), Jan P. Medema (Autor), Maurizio Bifulco (Autor), Patrizia Gazzerro (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2018-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Colorectal cancer (CRC), like other tumor types, is a highly heterogeneous disease. Within the tumor bulk, intra-tumoral heterogeneity is also ascribable to Cancer Stem Cells (CSCs) subpopulation, characterized by high chemoresistance and the unique ability to retain tumorigenic potential, thus asso...