Lipid Nanoparticle Inclusion Prevents Capsaicin-Induced TRPV1 Defunctionalization

• Asıl Yazarlar: Carmelo Puglia (Yazar), Debora Santonocito (Yazar), Angela Bonaccorso (Yazar), Teresa Musumeci (Yazar), Barbara Ruozi (Yazar), Rosario Pignatello (Yazar), Claudia Carbone (Yazar), Carmela Parenti (Yazar), Santina Chiechio (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2020-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Background: Capsaicin (CPS) is a highly selective agonist of the transient receptor potential vanilloid type 1 (TRPV1) with a nanomolar affinity. High doses or prolonged exposure to CPS induces TRPV1 defunctionalization and, although this effect is currently used for the treatment of thermal hyperal...