Endothelial Thioredoxin-Interacting Protein Depletion Reduces Hemorrhagic Transformation in Hyperglycemic Mice after Embolic Stroke and Thrombolytic Therapy

We hypothesize that endothelial-specific thioredoxin-interacting protein knock-out (EC-TXNIP KO) mice will be more resistant to the neurovascular damage (hemorrhagic-transformation-HT) associated with hyperglycemia (HG) in embolic stroke. Adult-male EC-TXNIP KO and wild-type (WT) littermate mice wer...

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Main Authors: Mohd. Salman (Author), Saifudeen Ismael (Author), Lexiao Li (Author), Heba A. Ahmed (Author), Michelle A. Puchowicz (Author), Tauheed Ishrat (Author)
Format: Book
Published: MDPI AG, 2021-09-01T00:00:00Z.
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3rd Floor Main Library

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