Endothelial Thioredoxin-Interacting Protein Depletion Reduces Hemorrhagic Transformation in Hyperglycemic Mice after Embolic Stroke and Thrombolytic Therapy

• मुख्य लेखकों: Mohd. Salman (लेखक), Saifudeen Ismael (लेखक), Lexiao Li (लेखक), Heba A. Ahmed (लेखक), Michelle A. Puchowicz (लेखक), Tauheed Ishrat (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2021-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

We hypothesize that endothelial-specific thioredoxin-interacting protein knock-out (EC-TXNIP KO) mice will be more resistant to the neurovascular damage (hemorrhagic-transformation-HT) associated with hyperglycemia (HG) in embolic stroke. Adult-male EC-TXNIP KO and wild-type (WT) littermate mice wer...