Endothelial Thioredoxin-Interacting Protein Depletion Reduces Hemorrhagic Transformation in Hyperglycemic Mice after Embolic Stroke and Thrombolytic Therapy

• Asıl Yazarlar: Mohd. Salman (Yazar), Saifudeen Ismael (Yazar), Lexiao Li (Yazar), Heba A. Ahmed (Yazar), Michelle A. Puchowicz (Yazar), Tauheed Ishrat (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

We hypothesize that endothelial-specific thioredoxin-interacting protein knock-out (EC-TXNIP KO) mice will be more resistant to the neurovascular damage (hemorrhagic-transformation-HT) associated with hyperglycemia (HG) in embolic stroke. Adult-male EC-TXNIP KO and wild-type (WT) littermate mice wer...