Cytokine response signatures in disease progression and development of severe clinical outcomes for leptospirosis.

• Hoofdauteurs: Eliana A G Reis (Auteur), José E Hagan (Auteur), Guilherme S Ribeiro (Auteur), Andrea Teixeira-Carvalho (Auteur), Olindo A Martins-Filho (Auteur), Ruth R Montgomery (Auteur), Albert C Shaw (Auteur), Albert I Ko (Auteur), Mitermayer G Reis (Auteur)
• Formaat: Boek
• Gepubliceerd in: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

<h4>Background</h4>The role of the immune response in influencing leptospirosis clinical outcomes is not yet well understood. We hypothesized that acute-phase serum cytokine responses may play a role in disease progression, risk for death, and severe pulmonary hemorrhage syndrome (SPHS)....