Histone deacetylase inhibitors relieve morphine resistance in neuropathic pain after peripheral nerve injury
Neuropathic pain is often insensitive to morphine. Our previous study has demonstrated that neuron-restrictive silencer factor represses mu opioid receptor (MOP) gene expression in the dorsal root ganglion (DRG) via histone hypoacetylation-mediated mechanisms after peripheral nerve injury, thereby c...
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Format: | Book |
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Elsevier,
2015-08-01T00:00:00Z.
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A1234.567 |
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