Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review

• Hoofdauteurs: Paolo E Porporato (Auteur), Rajesh K Dadhich (Auteur), Suveera eDhup (Auteur), Tamara eCopetti (Auteur), Pierre eSonveaux (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2011-08-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Cancer is a metabolic disease and the solution of two metabolic equations: to produce energy with limited resources and to fulfill the biosynthetic needs of proliferating cells. Both equations are solved when glycolysis is uncoupled from oxidative phosphorylation in the tricarboxylic acid cycle, a p...