Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review

• Main Authors: Paolo E Porporato (Author), Rajesh K Dadhich (Author), Suveera eDhup (Author), Tamara eCopetti (Author), Pierre eSonveaux (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer is a metabolic disease and the solution of two metabolic equations: to produce energy with limited resources and to fulfill the biosynthetic needs of proliferating cells. Both equations are solved when glycolysis is uncoupled from oxidative phosphorylation in the tricarboxylic acid cycle, a p...