Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review

• Prif Awduron: Paolo E Porporato (Awdur), Rajesh K Dadhich (Awdur), Suveera eDhup (Awdur), Tamara eCopetti (Awdur), Pierre eSonveaux (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2011-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Cancer is a metabolic disease and the solution of two metabolic equations: to produce energy with limited resources and to fulfill the biosynthetic needs of proliferating cells. Both equations are solved when glycolysis is uncoupled from oxidative phosphorylation in the tricarboxylic acid cycle, a p...