Molecular Disorder of Bicalutamide-Amorphous Solid Dispersions Obtained by Solvent Methods

• প্রধান লেখক: Joanna Szafraniec (লেখক), Agata Antosik (লেখক), Justyna Knapik-Kowalczuk (লেখক), Karolina Gawlak (লেখক), Mateusz Kurek (লেখক), Jakub Szlęk (লেখক), Witold Jamróz (লেখক), Marian Paluch (লেখক), Renata Jachowicz (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: MDPI AG, 2018-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The effect of solvent removal techniques on phase transition, physical stability and dissolution of bicalutamide from solid dispersions containing polyvinylpyrrolidone (PVP) as a carrier was investigated. A spray dryer and a rotavapor were applied to obtain binary systems containing either 50% or 66...