Triphenylphosphonium-modified mitochondria-targeted paclitaxel nanocrystals for overcoming multidrug resistance

• Hoofdauteurs: Xue Han (Auteur), Ruijuan Su (Auteur), Xiuqing Huang (Auteur), Yingli Wang (Auteur), Xiao Kuang (Auteur), Shuang Zhou (Auteur), Hongzhuo Liu (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2019-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Mitochondria are currently known as novel targets for treating cancer, especially for tumors displaying multidrug resistance (MDR). This present study aimed to develop a mitochondria-targeted delivery system by using triphenylphosphonium cation (TPP+)-conjugated Brij 98 as the functional stabilizer...