Triphenylphosphonium-modified mitochondria-targeted paclitaxel nanocrystals for overcoming multidrug resistance

• Главные авторы: Xue Han (Автор), Ruijuan Su (Автор), Xiuqing Huang (Автор), Yingli Wang (Автор), Xiao Kuang (Автор), Shuang Zhou (Автор), Hongzhuo Liu (Автор)
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• Опубликовано: Elsevier, 2019-09-01T00:00:00Z.
• Предметы: article
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Mitochondria are currently known as novel targets for treating cancer, especially for tumors displaying multidrug resistance (MDR). This present study aimed to develop a mitochondria-targeted delivery system by using triphenylphosphonium cation (TPP+)-conjugated Brij 98 as the functional stabilizer...