Evaluation of Approaches for the Assessment of HER2 Expression in Breast Cancer by Radionuclide Imaging Using the Scaffold Protein [^99mTc]Tc-ADAPT6

• Asıl Yazarlar: Olga Bragina (Yazar), Liubov Tashireva (Yazar), Dmitriy Loos (Yazar), Vladimir Chernov (Yazar), Sophia Hober (Yazar), Vladimir Tolmachev (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2024-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Due to its small size and high affinity binding, the engineered scaffold protein ADAPT6 is a promising targeting probe for radionuclide imaging of human epidermal growth factor receptor type 2 (HER2). In a Phase I clinical trial, [^99mTc]Tc-ADAPT6 demonstrated safety, tolerabil...