Evaluation of Approaches for the Assessment of HER2 Expression in Breast Cancer by Radionuclide Imaging Using the Scaffold Protein [^99mTc]Tc-ADAPT6

• 主要な著者: Olga Bragina (著者), Liubov Tashireva (著者), Dmitriy Loos (著者), Vladimir Chernov (著者), Sophia Hober (著者), Vladimir Tolmachev (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2024-03-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Due to its small size and high affinity binding, the engineered scaffold protein ADAPT6 is a promising targeting probe for radionuclide imaging of human epidermal growth factor receptor type 2 (HER2). In a Phase I clinical trial, [^99mTc]Tc-ADAPT6 demonstrated safety, tolerabil...