Effects of Protein Kinase A on the Phosphorylation Status and Transverse Stiffness of Cardiac Myofibrils

• Hauptverfasser: Yoshiki Ohnuki (Verfasst von), Takenori Yamada (Verfasst von), Yasumasa Mototani (Verfasst von), Daisuke Umeki (Verfasst von), Kouichi Shiozawa (Verfasst von), Takayuki Fujita (Verfasst von), Yasutake Saeki (Verfasst von), Satoshi Okumura (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2013-01-01T00:00:00Z.
• Schlagworte: article
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Stimulation of β-adrenergic receptors in cardiac myocytes activates cyclic AMP- dependent protein kinase A (PKA). PKA-mediated phosphorylation of myofibrils decreases their longitudinal stiffness, but its effect on transverse stiffness is not fully understood. We thus examined the effects of PKA tre...