CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia

• Главные авторы: Xiao Liu (Автор), Lili Zhang (Автор), Yueying Yang (Автор), Weiwei Yin (Автор), Yunhu Liu (Автор), Chunyi Luo (Автор), Ruizhe Zhang (Автор), Zhiguo Long (Автор), Yanyan Jiang (Автор), Bing Wang (Автор)
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• Опубликовано: Elsevier, 2023-07-01T00:00:00Z.
• Предметы: article
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Clinically, arsenic trioxide (ATO) was applied to the treatment of acute promyelocytic leukemia (APL) as a reliable and effective frontline drug. However, the administration regimen of AsⅢ was limited due to its fast clearance, short therapeutic window and toxicity as well. Based on CD71 overexpress...