CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia

• Main Authors: Xiao Liu (Author), Lili Zhang (Author), Yueying Yang (Author), Weiwei Yin (Author), Yunhu Liu (Author), Chunyi Luo (Author), Ruizhe Zhang (Author), Zhiguo Long (Author), Yanyan Jiang (Author), Bing Wang (Author)
• Format: Book
• Published: Elsevier, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Clinically, arsenic trioxide (ATO) was applied to the treatment of acute promyelocytic leukemia (APL) as a reliable and effective frontline drug. However, the administration regimen of AsⅢ was limited due to its fast clearance, short therapeutic window and toxicity as well. Based on CD71 overexpress...