Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum.

• Auteurs principaux: John B Patton (Auteur), Sasisekhar Bennuru (Auteur), Mark L Eberhard (Auteur), Jessica A Hess (Auteur), April Torigian (Auteur), Sara Lustigman (Auteur), Thomas B Nutman (Auteur), David Abraham (Auteur)
• Format: Livre
• Publié: Public Library of Science (PLoS), 2018-12-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

<h4>Background</h4>The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the development of adult parasites have not been identified.<h4>...