Multiple mitochondrial introgression events and heteroplasmy in trypanosoma cruzi revealed by maxicircle MLST and next generation sequencing.

• Κύριοι συγγραφείς: Louisa A Messenger (Συγγραφέας), Martin S Llewellyn (Συγγραφέας), Tapan Bhattacharyya (Συγγραφέας), Oscar Franzén (Συγγραφέας), Michael D Lewis (Συγγραφέας), Juan David Ramírez (Συγγραφέας), Hernan J Carrasco (Συγγραφέας), Björn Andersson (Συγγραφέας), Michael A Miles (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Mitochondrial DNA is a valuable taxonomic marker due to its relatively fast rate of evolution. In Trypanosoma cruzi, the causative agent of Chagas disease, the mitochondrial genome has a unique structural organization consisting of 20-50 maxicircles (∼20 kb) and thousands of minicircles (0.5-10 kb)....