Multiple mitochondrial introgression events and heteroplasmy in trypanosoma cruzi revealed by maxicircle MLST and next generation sequencing.

• Glavni autori: Louisa A Messenger (Autor), Martin S Llewellyn (Autor), Tapan Bhattacharyya (Autor), Oscar Franzén (Autor), Michael D Lewis (Autor), Juan David Ramírez (Autor), Hernan J Carrasco (Autor), Björn Andersson (Autor), Michael A Miles (Autor)
• Format: Knjiga
• Izdano: Public Library of Science (PLoS), 2012-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Mitochondrial DNA is a valuable taxonomic marker due to its relatively fast rate of evolution. In Trypanosoma cruzi, the causative agent of Chagas disease, the mitochondrial genome has a unique structural organization consisting of 20-50 maxicircles (∼20 kb) and thousands of minicircles (0.5-10 kb)....