A novel case of prolonged Ifosfamide encephalopathy and long-term treatment with methylene blue: a case report and review of literature

• Главные авторы: Gabriel Chain (Автор), Mudit Kalia (Автор), Karen Kestenbaum (Автор), Lara Pappas (Автор), Anna Sechser-Perl (Автор), Gadi Abebe Campino (Автор), Nibal Zaghloul (Автор)
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• Опубликовано: BMC, 2022-02-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background Encephalopathy following Ifosfamide treatment is a well-described phenomenon that is typically treated with Methylene Blue (MB). Chloroacetaldehyde, a potentially neurotoxic metabolite of Ifosfamide is hypothesized to cause this encephalopathy. Current guidelines for treatment is...