A novel case of prolonged Ifosfamide encephalopathy and long-term treatment with methylene blue: a case report and review of literature

• Main Authors: Gabriel Chain (Author), Mudit Kalia (Author), Karen Kestenbaum (Author), Lara Pappas (Author), Anna Sechser-Perl (Author), Gadi Abebe Campino (Author), Nibal Zaghloul (Author)
• Format: Book
• Published: BMC, 2022-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Encephalopathy following Ifosfamide treatment is a well-described phenomenon that is typically treated with Methylene Blue (MB). Chloroacetaldehyde, a potentially neurotoxic metabolite of Ifosfamide is hypothesized to cause this encephalopathy. Current guidelines for treatment is...