Utilization of the Drug-Polymer Solid Dispersion Obtained by Ball Milling as a Taste Masking Method in the Development of Orodispersible Minitablets with Hydrocortisone in Pediatric Doses

• Main Authors: Monika Trofimiuk (Author), Katarzyna Olechno (Author), Emil Trofimiuk (Author), Anna Czajkowska-Kośnik (Author), Patrycja Ciosek-Skibińska (Author), Klaudia Głowacz (Author), Joanna Lenik (Author), Anna Basa (Author), Halina Car (Author), Katarzyna Winnicka (Author)
• Format: Book
• Published: MDPI AG, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The objective of the conducted research was to design 2 mm orodispersible minitablets of pediatric doses of hydrocortisone (0.5 mg; 1.0 mg) with desirable pharmaceutical properties and eliminate the sensation of a bitter taste using preparation of solid dispersion by ball mill. Hydrocortisone was se...