Utilization of the Drug-Polymer Solid Dispersion Obtained by Ball Milling as a Taste Masking Method in the Development of Orodispersible Minitablets with Hydrocortisone in Pediatric Doses

• Principais autores: Monika Trofimiuk (Autor), Katarzyna Olechno (Autor), Emil Trofimiuk (Autor), Anna Czajkowska-Kośnik (Autor), Patrycja Ciosek-Skibińska (Autor), Klaudia Głowacz (Autor), Joanna Lenik (Autor), Anna Basa (Autor), Halina Car (Autor), Katarzyna Winnicka (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2024-08-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

The objective of the conducted research was to design 2 mm orodispersible minitablets of pediatric doses of hydrocortisone (0.5 mg; 1.0 mg) with desirable pharmaceutical properties and eliminate the sensation of a bitter taste using preparation of solid dispersion by ball mill. Hydrocortisone was se...