Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanisms

• Main Authors: Cristina eFenollar Ferrer (Author), Ariela eVergara Jaque (Author), Desirée eKaufmann (Author), Lucy Rachel Forrest (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Secondary active transporters are critical for neurotransmitter clearance and recycling during synaptic transmission and uptake of nutrients. These proteins mediate the movement of solutes against their concentration gradients, by using the energy released in the movement of ions down pre-existing c...