Repeat-swap homology modeling of secondary active transporters: updated protocol and prediction of elevator-type mechanisms

• Главные авторы: Cristina eFenollar Ferrer (Автор), Ariela eVergara Jaque (Автор), Desirée eKaufmann (Автор), Lucy Rachel Forrest (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2015-09-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Secondary active transporters are critical for neurotransmitter clearance and recycling during synaptic transmission and uptake of nutrients. These proteins mediate the movement of solutes against their concentration gradients, by using the energy released in the movement of ions down pre-existing c...