Self-nanoemulsifying System Optimization for Higher Terconazole Solubilization and Non-Irritant Ocular Administration

• Main Authors: Carol Yousry (Author), Pakinam Mohsen Zikry (Author), Emad Basalious Basalious (Author), Omaima Naem El-Gazayerly (Author)
• פורמט: ספר
• יצא לאור: Tabriz University of Medical Sciences, 2020-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Purpose: Eye drops' formulations of poorly water-soluble drugs, offer the advantage of crossing the lipophilic cornea, but their limited aqueous solubility may lead to low ocular bioavailability limiting their therapeutic uses. Terconazole (TZ) is an antifungal drug with low aqueous solubility,...