A yeast model for amyloid-β aggregation exemplifies the role of membrane trafficking and PICALM in cytotoxicity

• Váldodahkkit: Fabien D'Angelo (Dahkki), Hélène Vignaud (Dahkki), Julie Di Martino (Dahkki), Bénédicte Salin (Dahkki), Anne Devin (Dahkki), Christophe Cullin (Dahkki), Christelle Marchal (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: The Company of Biologists, 2013-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

SUMMARY Alzheimer's disease is the most common neurodegenerative disease, associated with aggregation of amyloid-β (Aβ) peptides. The exact mechanism of neuronal cell dysfunction in Alzheimer's disease is poorly understood and numerous models have been used to decipher the mechanisms leadi...