Emerging Effects of Sepantronium Bromide (YM155) on MOLT-4 Cell Line Apoptosis Induction and Expression of Critical Genes Involved in Apoptotic Pathways

• Asıl Yazarlar: Kobra Shojaei Moghadam (Yazar), Majid Farshdousti Hagh (Yazar), Mohammad Reza Alivand (Yazar), Masoumeh Fardi (Yazar), Ali Akbar Movassaghpour (Yazar), Ali Mohammadi (Yazar), Maryam Moghadasi (Yazar), Saeed Solali (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Tabriz University of Medical Sciences, 2020-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Purpose: Sepantronium bromide (YM155) is a Survivin inhibitor which recently advanced as an anticancer agent in phase II clinical trials. Survivin belongs to IAP (inhibitor of apoptosis) gene family and is a pivotal target for treatment due to its overexpression and oncogenic function in many malign...