The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development

• Main Authors: Sebastian Gehlen-Breitbach (Author), Theresa Schmid (Author), Franziska Fröb (Author), Gabriele Rodrian (Author), Matthias Weider (Author), Michael Wegner (Author), Lina Gölz (Author)
• Format: Book
• Published: Nature Publishing Group, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The cranial neural crest plays a fundamental role in orofacial development and morphogenesis. Accordingly, mutations with impact on the cranial neural crest and its development lead to orofacial malformations such as cleft lip and palate. As a pluripotent and dynamic cell population, the cr...