The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development

• Principais autores: Sebastian Gehlen-Breitbach (Autor), Theresa Schmid (Autor), Franziska Fröb (Autor), Gabriele Rodrian (Autor), Matthias Weider (Autor), Michael Wegner (Autor), Lina Gölz (Autor)
• Formato: Livro
• Publicado em: Nature Publishing Group, 2023-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract The cranial neural crest plays a fundamental role in orofacial development and morphogenesis. Accordingly, mutations with impact on the cranial neural crest and its development lead to orofacial malformations such as cleft lip and palate. As a pluripotent and dynamic cell population, the cr...