The Tip60/Ep400 chromatin remodeling complex impacts basic cellular functions in cranial neural crest-derived tissue during early orofacial development

• Главные авторы: Sebastian Gehlen-Breitbach (Автор), Theresa Schmid (Автор), Franziska Fröb (Автор), Gabriele Rodrian (Автор), Matthias Weider (Автор), Michael Wegner (Автор), Lina Gölz (Автор)
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• Опубликовано: Nature Publishing Group, 2023-04-01T00:00:00Z.
• Предметы: article
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Abstract The cranial neural crest plays a fundamental role in orofacial development and morphogenesis. Accordingly, mutations with impact on the cranial neural crest and its development lead to orofacial malformations such as cleft lip and palate. As a pluripotent and dynamic cell population, the cr...