Evaluation of pH-Sensitive Polymeric Micelles Using Citraconic Amide Bonds for the Co-Delivery of Paclitaxel, Etoposide, and Rapamycin

• Κύριοι συγγραφείς: Min Jeong Jo (Συγγραφέας), Hee Ji Shin (Συγγραφέας), Moon Sup Yoon (Συγγραφέας), Seo Yeon Kim (Συγγραφέας), Chae Eun Jin (Συγγραφέας), Chun-Woong Park (Συγγραφέας), Jin-Seok Kim (Συγγραφέας), Dae Hwan Shin (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: MDPI AG, 2023-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Paclitaxel (PTX), etoposide (ETP), and rapamycin (RAPA) have different mechanisms, allowing multiple pathways to be targeted simultaneously, effectively treating various cancers. However, these drugs have a low hydrosolubility, limiting clinical applications. Therefore, we used pH-sensitive polymeri...