Sigma-1 Receptor Plays a Negative Modulation on N-type Calcium Channel

• Hauptverfasser: Kang Zhang (VerfasserIn), Zhe Zhao (VerfasserIn), Liting Lan (VerfasserIn), Xiaoli Wei (VerfasserIn), Liyun Wang (VerfasserIn), Xiaoyan Liu (VerfasserIn), Haitao Yan (VerfasserIn), Jianquan Zheng (VerfasserIn)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

The sigma-1 receptor is a 223 amino acids molecular chaperone with a single transmembrane domain. It is resident to eukaryotic mitochondrial-associated endoplasmic reticulum and plasma membranes. By chaperone-mediated interactions with ion channels, G-protein coupled receptors and cell-signaling mol...