GPR35 antagonist CID-2745687 attenuates anchorage-independent cell growth by inhibiting YAP/TAZ activity in colorectal cancer cells

Background and purpose: GPR35, a member of the orphan G-protein-coupled receptor, was recently implicated in colorectal cancer (CRC). However, whether targeting GPR35 by antagonists can inhibit its pro-cancer role has yet to be answered.Experimental approach: We applied antagonist CID-2745687 (CID)...

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Main Authors: Wuxiyar Otkur (Author), Xiaolong Liu (Author), Huan Chen (Author), Siyi Li (Author), Ting Ling (Author), Hanchen Lin (Author), Renyu Yang (Author), Tian Xia (Author), Huan Qi (Author), Hai-Long Piao (Author)
Format: Book
Published: Frontiers Media S.A., 2023-04-01T00:00:00Z.
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