Dual Role of Dietary Curcumin Through Attenuating AFB1-Induced Oxidative Stress and Liver Injury via Modulating Liver Phase-I and Phase-II Enzymes Involved in AFB1 Bioactivation and Detoxification

• المؤلفون الرئيسيون: Ishfaq Muhammad (مؤلف), He Wang (مؤلف), Xiaoqi Sun (مؤلف), Xinghe Wang (مؤلف), Meiyu Han (مؤلف), Ziyin Lu (مؤلف), Ping Cheng (مؤلف), Muhammad A. Hussain (مؤلف), Xiuying Zhang (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2018-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

It is well understood that liver cytochrome p450 enzymes are responsible for AFB1 bioactivation, while phase-II enzymes regulated by the transcription factor nuclear factor-erythroid-2-related factor 2 (Nrf2) are involved in detoxification of AFB1. In this study, we explored the potential of curcumi...