Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice.

• Príomhchruthaitheoirí: Lynn Soong (Údar), Thomas R Shelite (Údar), Yan Xing (Údar), Harica Kodakandla (Údar), Yuejin Liang (Údar), Brandon J Trent (Údar), Paulina Horton (Údar), Kathryn C Smith (Údar), Zhenyang Zhao (Údar), Jiaren Sun (Údar), Donald H Bouyer (Údar), Jiyang Cai (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Public Library of Science (PLoS), 2017-07-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

BACKGROUND:Scrub typhus is a life-threatening disease, due to infection with O. tsutsugamushi, a Gram-negative bacterium that preferentially replicates in endothelial cells and professional phagocytes. Meningoencephalitis has been reported in scrub typhus patients and experimentally-infected animals...