Acid-Sensitive Sheddable PEGylated PLGA Nanoparticles Increase the Delivery of TNF-α siRNA in Chronic Inflammation Sites

• Asıl Yazarlar: Abdulaziz M Aldayel (Yazar), Youssef W Naguib (Yazar), Hannah L O'Mary (Yazar), Xu Li (Yazar), Mengmeng Niu (Yazar), Tinashe B Ruwona (Yazar), Zhengrong Cui (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2016-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

There has been growing interest in utilizing small interfering RNA (siRNA) specific to pro-inflammatory cytokines, such as tumor necrosis factor-α (TNF-α), in chronic inflammation therapy. However, delivery systems that can increase the distribution of the siRNA in chronic inflammation sites after i...