Antidepressants Fluoxetine Mediates Endoplasmic Reticulum Stress and Autophagy of Non-Small Cell Lung Cancer Cells Through the ATF4-AKT-mTOR Signaling Pathway

Fluoxetine, one of the latest clinical antidepressants, is reported to have the anti-proliferative effect on cancer cells via immune-related pathways. However, the mechanism is still not known. This study mainly focused on the discovery of the molecular basis of the inhibitory effect of fluoxetine i...

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Main Authors: Shali Shao (Author), Xibing Zhuang (Author), Lin Zhang (Author), Tiankui Qiao (Author)
Format: Book
Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
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