Antidepressants Fluoxetine Mediates Endoplasmic Reticulum Stress and Autophagy of Non-Small Cell Lung Cancer Cells Through the ATF4-AKT-mTOR Signaling Pathway

• المؤلفون الرئيسيون: Shali Shao (مؤلف), Xibing Zhuang (مؤلف), Lin Zhang (مؤلف), Tiankui Qiao (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Fluoxetine, one of the latest clinical antidepressants, is reported to have the anti-proliferative effect on cancer cells via immune-related pathways. However, the mechanism is still not known. This study mainly focused on the discovery of the molecular basis of the inhibitory effect of fluoxetine i...