Transcription factor IRF1 is responsible for IRF8-mediated IL-1β expression in reactive microglia
Interferon regulatory factor-8 (IRF8) plays a crucial role in the transformation of microglia to a reactive state by regulating the expression of various genes. In the present study, we show that IRF1 is required for IRF8-induced gene expression in microglia. Peripheral nerve injury induced IRF1 gen...
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| Main Authors: | , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2015-08-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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