The potential influence of estrogen-containing oral contraception on clozapine metabolism in a patient with known pharmacogenomic status
Clozapine is primarily metabolized via cytochrome P450(CYP)1A2 and to a lesser extent CYP3A4, CYP2C19, and CYP2D6. Metabolic inhibitors of clozapine, such as fluvoxamine and ciprofloxacin, are important to recognize to avoid adverse drug events. Estrogen-containing oral contraceptives (eOCPs) are we...
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American Association of Psychiatric Pharmacists,
2024-06-01T00:00:00Z.
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A1234.567 |
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