The potential influence of estrogen-containing oral contraception on clozapine metabolism in a patient with known pharmacogenomic status

Clozapine is primarily metabolized via cytochrome P450(CYP)1A2 and to a lesser extent CYP3A4, CYP2C19, and CYP2D6. Metabolic inhibitors of clozapine, such as fluvoxamine and ciprofloxacin, are important to recognize to avoid adverse drug events. Estrogen-containing oral contraceptives (eOCPs) are we...

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Main Authors: Alyssa K. Kuhn (Author), Meina L. Determan (Author), Jessica A. Wright, PharmD (Author), Eric Matey (Author), Jonathan G. Leung (Author)
Format: Book
Published: American Association of Psychiatric Pharmacists, 2024-06-01T00:00:00Z.
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